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Yakachena Dalbergia Odoriferae Lignum mafuta ekenduru nesipo inogadzira maholese diffuser akakosha mafuta matsva ekupisa tsanga diffuser.
Mushonga wemushongaDalbergia odoriferaT. Chen marudzi, anonziwoLignum Dalbergia odoriferae[1], ndeye genusDalbergia, mhuri Fabaceae (Leguminosae) [2]. Chirimwa ichi chakaparadzirwa zvakanyanya munzvimbo dzinopisa dzeCentral neSouth America, Africa, Madagascar, uye East and Southern Asia [1,3], kunyanya kuChina [4].D. odoriferamhando, iyo yave ichizivikanwa se "Jiangxiang" muchiChinese, "Kangjinhyang" muchiKorea, uye "Koshinko" mumishonga yechiJapan, yakashandiswa mukurapa kwechivanhu kurapa hosha dzemoyo, kenza, chirwere cheshuga, kusagadzikana kweropa, ischemia, kuzvimba. necrosis, rheumatic kurwadziwa, zvichingodaro [5-7]. Kunyanya, kubva kuChinese herbal kugadzirira, heartwood yakawanikwa uye yave ichiwanzo shandiswa sechikamu chekutengesa zvinodhaka zvinodhaka zvekurapwa kwemoyo, kusanganisira Qi-Shen-Yi-Qi decoction, Guanxin-Danshen mapiritsi, uye Danshen jekiseni [5,6,8-11]. Sezvimwe zvakawandaDalbergiamhando, phytochemical research yakaratidza kuitika kweiyo yakawanda flavonoid, phenol, uye sesquiterpene zvinobva munzvimbo dzakasiyana dzechirimwa ichi, kunyanya maererano neheartwood [12]. Uyezve, nhamba yezvinyorwa zvebioactive nezve cytotoxic, antibacterial, antioxidative, anti-inflammatory, antithrombotic, antiosteosarcoma, antiosteoporosis, uye vasorelaxant zviitiko uye alpha-glucosidase inhibitory zviitiko zvinoratidza kuti zvose zviri zviviri.D. odoriferacrude extracts uye yechipiri metabolites zvinhu zvakakosha zvekugadzirwa kwemishonga mitsva. Nekudaro, hapana humbowo hwakashumwa hwemaonero akajairwa nezvechirimwa ichi. Muongororo iyi, tinopa tarisiro yezvakakura zvemakemikari zvikamu uye biological ongororo. Ongororo iyi yaizobatsira pakunzwisisa tsika dzechinyakare dzeD. odoriferanemamwe marudzi ane hukama, uye inopa nhungamiro inodiwa yetsvagurudzo yeramangwana.
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Wholesale Yakachena Natural Atractylodes Lancea Mafuta eZuva Remazuva Chemakemikari Indasitiri Herb Extract Atractylis Oil
MASHOKO OKUSHANDISA UYE RUZIVO RWAKAKOSHA: Ruzivo urwu rwunoitirwa kuwedzera, kwete kutsiva zano kubva kuna chiremba wako kana mutapi wehutano uye harina kuitirwa kuvhara zvese zvinogona kushandiswa, chenjedzo, kudyidzana kana mhedzisiro yakaipa. Ruzivo urwu runogona kusaenderana nemamiriro ako ehutano. Usambofa wakanonoka kana kuregeredza kutsvaga mazano ekurapa kubva kuna chiremba wako kana mumwe mupi wehutano ane hunyanzvi nekuda kwechimwe chinhu chawakaverenga paWebMD. Iwe unofanirwa kugara uchitaura nachiremba wako kana nyanzvi yezvehutano usati watanga, kumira, kana kushandura chero chikamu chakatemwa cheurongwa hwehutano hwako kana kurapwa uye kuona kuti ndeipi nzira yekurapa yakakunakira iwe.
Izvi zvinyorwa zvekodzero zvinopihwa ne Natural Medicines Comprehensive Database Consumer Version. Ruzivo kubva kune ino sosi umbowo-hwakavakirwa uye chinangwa, uye pasina kutengeserana pesvedzero. Kuti uwane ruzivo rwezvechiremba nezvemishonga yechisikigo, ona Natural Medicines Comprehensive Database Professional Version.
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Wholesale Yakachena Natural Atractylodes Lancea Mafuta eZuva Remazuva Chemakemikari Indasitiri Herb Extract Atractylis Oil
Chii chinonzi Atractylodes lancea root extract?
Atractylodes lancea chiChinese chinobva, chirimwa chakakosha chemushonga, chinorimwa nekuda kwema rhizomes. Marhizomes ayo ane mafuta anokosha.
Kushandisa & Benefits:
Iine anti-inflammatory properties, inonyaradza ganda kana yakashandiswa. Inogona kubatsira kune acne, ganda rinotsamwisa.
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Menthol CamphorBorneol Oiri Yemukati Yekugezesa Uye Aromatherapy
Utano Benefits uye Mashandisirwo
Borneol inopa mharadzano inobatsira kwazvo yemushonga wekuMadokero nekuMabvazuva. Mhedzisiro yeBorneol yakapararira mukurapa kwezvirwere zvakasiyana-siyana. MuChinese Medicine, inosanganiswa nechiropa, spleen meridians, mwoyo, uye mapapu. Pazasi pane rondedzero yezvimwe zvezvakawanda zvehutano zvinobatsira.
Inorwisa chirwere chekufema uye chirwere chemapapu
Zvidzidzo zvakawanda zvinoratidza terpenes, uye Borneol, kunyanya, inoderedza kurwara kwekufema. Borneol ineyakaratidza kushandamukuderedza kuzvimba kwemapapu nekuderedza kuputika kwe cytokines uye kupinda mukati. Vanhu vanodzidzira Chinese Medicine vanowanzo shandisa Borneol kurapa bronchitis nezvimwe zvirwere zvakafanana.
Anticancer properties
Borneol yakaratidzawoanticancer propertiesnekuwedzera chiito cheSelenocysteine (SeC). Izvi zvakaderedza gomarara rinopararira kuburikidza neapoptotic (yakarongwa) cancer cell kufa. Muzvidzidzo zvakawanda, Borneol yakaratidzawo kuwedzera kushanda kweantitumor drug targeting.
Kushanda analgesic
Mune akudzidzatichifunga nezvekurwadziwa kwepashure muvanhu, topical Borneol application yakakonzera kuderera kukuru kwemarwadzo kana ichienzaniswa neboka rekudzora placebo. Pamusoro pezvo, ma acupuncturists anowanzo kushandisa Borneol kumusoro kune ayo analgesic zvimiro.
Anti-inflammatory action
Borneol ineakaratidzakuvhara dzimwe nzira dzeion dzinokurudzira kukurudzira marwadzo uye kuzvimba. Inobatsirawo mukugadzirisa marwadzo kubva kune zvirwere zvinoputika zvakadai serheumatoid arthritis.
Neuroprotective madhara
Borneol inopa imwe dziviriro kubvaneuronal cell kufakana paine ischemic stroke. Inobatsirawo kuvandudzwa kwehuropi tishu uye kugadzirisa. Inokurudzirwa kuve neiyi neuroprotective mhedzisiro nekuchinja kupemerwa kweiyoropa-uropi chipingamupinyi.
Inorwisa kushushikana uye kuneta
Vamwe vashandisi ve cannabis strains ane akakwira Borneol mazinga anoratidza kuti inoderedza kushushikana kwavo uye inoderedza kuneta, nekudaro, ichibvumira mamiriro ekuzorora pasina kuzara sedation. Vanhu vanoita zveChinese Medicine vanobvumawoits stress relief potential.
Entourage effect
Sezvimwe nemamwe terpenes, mhedzisiro yeBorneol pamwe neiyo cannabinoids ye cannabis yakaratidza.entourage effect.Izvi zvinoitika kana makomboni anoshanda pamwechete kuti ape kumwe kukwidziridzwa kwekurapa. Borneol inogona kuwedzera ropa-brain barriers permeability, zvichibvumira kupfuudza nyore kwemamorekuru ekurapa kune yepakati tsinga system.
Kunze kweBorneol yakawanda yemishonga yemishonga, inowanzoshandiswa mumishonga inodzinga zvipembenene nekuda kwehusikirwo hwayo hwehuputi kune dzakawanda. Perfumeries inoshandurawo Borneol nekuda kwekunhuhwirira kwayo kune vanhu.
Njodzi Dzinogona Kuitika uye Migumisiro Yakashata
Borneol inowanzoonekwa sechipiri terpene mu cannabis, zvichireva kuti inoratidzika muhuwandu hudiki. Aya madosi epasi eBorneol anofungidzirwa kuti haana kuchengeteka. Nekudaro, mune yakasarudzika madosi akakwira kana kuratidzwa kwenguva refu, Borneol inogona kuve nezvimwenjodzi dzinogona kuitika nemhedzisiro, kusanganisira:
- Kushatirwa kweganda
- Kushatirwa kwemhino nehuro
- Headache
- Nausea uye kurutsa
- Dzungu
- Chiedza-musoro
- Kufenda
Nekuratidzwa kwakanyanya kweBorneol, vanhu vanogona kuwana:
- Kusagadzikana
- Kushungurudzika
- Kusateerera
- Kubatwa nepfari
- Kana ikamedzwa, inogona kuva muchetura zvakanyanya
Izvo zvakakosha kuti uzive kuti huwandu huripo mu cannabis haagone kukonzera izvi zviratidzo. Kushatirwa zvakare hakuitike pamwe nediki madosi anoshandiswa kuanalgesia uye zvimwe zvinokonzeresa.
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Pure Cnidii Fructus mafuta ekenduru uye sipo kugadzira wholesale diffuser yakakosha mafuta matsva ekupisa tsanga diffuser.
Cnidium chirimwa chinobva kuChina. Yakawanikwa zvakare muUS muOregon. Muchero, mbeu, uye zvimwe zvikamu zvechirimwa zvinoshandiswa semushonga.
Cnidium yakashandiswa muTraditional Chinese Medicine (TCM) kwezviuru zvemakore, kazhinji kune mamiriro eganda. Hazvishamisi kuti cnidium chinhu chinowanikwa muChinese lotions, creams, uye mafuta.
Vanhu vanotora cnidium nemuromo yekuwedzera kuita zvepabonde uye kuita zvepabonde, uye nekurapa erectile dysfunction (ED). Cnidium inoshandiswawo kuomerwa nevana (kusabereka), kuvaka muviri, kenza, mapfupa asina simba (osteoporosis), uye fungal uye bhakitiriya zvirwere. Vamwe vanhu vanotorawo kuti vawedzere simba.
Cnidium inoshandiswa zvakananga paganda kuitira kuputika, kuputika, eczema, uye ringworm.
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Kemikari yakagadzirwa ATR
Iko kemikari yeATR inonyanya kushanduka zvikamu uye zvisingagadziriswi zvikamu. Iyo ATR yakakosha mafuta (ATEO) inoonekwa sechinhu chinoshanda cheATR, uye zvirimo muATEO ndiyo chete chiratidzo chekutemerwa kweATR yemukati. Parizvino, kune tsvakiridzo dzakasiyana-siyana pazvikamu zvinoshanduka uye netsvakiridzo shoma pazvikamu zvisingaite. Izvo zvikamu zvinoputika zvinenge zvakaoma, uye maitiro makuru emhando ndeye phenylpropanoids (nyore phenylpropanoids, lignans uye coumarins) uye terpenoids (monoterpenes, sesquiterpenes, diterpenoids uye triterpenes). Zvisiri-zvinoshanduka zvinoumba alkaloids, aldehydes uye acids, quinones uye ketones, sterols, amino acids, uye makabhohaidhiretsi. Mhedzisiro yeATR yemakemikari ekuumbwa kudzidza inozobatsira mukuvandudza kwayo kwemhando yekutsvagisa.
Volatile composition
Vatsvakurudzi vakashandisa nzira dzekuongorora dzekuongorora dzakadai sechromatography uye GC-MS kuongorora zvikamu zvemakemikari zveATR kubva kwakasiyana mavambo, mabheti akasiyana, nzira dzakasiyana dzekuchera uye zvikamu zvakasiyana. Zvidzidzo zvakapfuura zvakaratidza kuti makemikari makuru ari muATR aive mafuta anopisa, ayo ari chiratidzo chakakosha chekuongororwa kwemhando yeATR. α-Asarone uye β-asarone yakaverengera 95% yeATR inoputika mafuta uye yakaonekwa semhando yezvikamu (Mufananidzo 1) (Lam et al., 2016a) Iyo "Pharmacopoeia yeThe People's Republic of China" (2020 Edition) inorekodha kuti mafuta anopisa ari muATR haafanire kunge ari pasi pe1.0% (mL/g). Parizvino, marudzi akawanda emafuta anopisa anowanikwa muATR
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Perilla muriwo. Shizha nemhodzi zvinoshandiswa kugadzira mushonga.
Perilla inoshandiswa kurapa asima. Inoshandiswawo kusvotwa, kupisa kwezuva, kudikitira, uye kuderedza tsinga dzetsandanyama.
Muchikafu, perilla inoshandiswa sechinhu chinonhuwira.
Mukugadzira, mafuta embeu yeperilla anoshandiswa mukutengesa mukugadzirwa kwemavarnish, madhayi, neingi.
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Angelica chirimwa. Mudzi, mbeu, uye muchero zvinoshandiswa kugadzira mushonga.
Angelica inoshandiswa kurwisa chirungurira, gasi remudumbu (flatulence), kurasikirwa kwechido (anorexia), arthritis, matambudziko ekutenderera, "runny mhino" (kufema catarrh), kutya, denda, uye kunetseka kurara (kusarara).
Vamwe vakadzi vanoshandisa Angelica kutanga kuenda kumwedzi. Dzimwe nguva izvi zvinoitwa kuti abvise pamuviri.
Angelica inoshandiswawo kuwedzera kugadzirwa kweweti, kunatsiridza bonde, kukurudzira kugadzirwa uye kubuda kwephlegm, uye kuuraya utachiona.
Vamwe vanhu vanoisa Angelica zvakananga paganda nokuda kwemarwadzo etsinga (neuralgia), kurwadziwa kwemajoini (rheumatism), uye zvirwere zveganda.
Mukubatana nemamwe maruva, Angelica inoshandiswawo kurapa nguva isati yakwana.
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100% Yakachena Herbal Essential Cyperus Oiri yeSipo Kugadzira Cyperus Rotundus Mafuta
Nutgrass igwenzi rine mukurumbira rinoshandiswa pamhando dzakawanda dzekuchengetedza ganda. Sekureva kweAyurveda, yakashandiswa mumakononi akasiyana siyana akagadzirirwa kuvheneka nzvimbo dzakasviba nezvimwe.
Benefits…
Yakawanikwa zvakare mumishonga yakawanda yeAyurvedic yekurapa rashes, fungal zvirwere uye mamiriro eganda. Iwo akaomeswa ehupfu emudzi weNutgrass ane simba zvakanyanya uye akapfumiswa ne antioxidants, ayo anobatsira kunonotsa kuchembera kweganda sezvo ichishanda kudzikisa mitsetse yakanaka nemakwinya. Inobatsira kudzora kuumbwa kwakanyanya kwe pigment, melanin, muganda. Nekudaro inodzoreredza kupenya kweganda. Nutgrass iri kutonhora muzvisikwa, iyo anti-kuzvimba pfuma inobatsira kunyaradza kutsvuka, kuputika, uye ganda rinopisa. Yakaratidza kurapa yakaoma ganda mamiriro. Yakapfuma mumafuta acids, mavhitamini uye flavonoids ayo anobatsira zvakanyanya paganda pamwe nebvudzi. Zvinhu izvi zvinowedzera kupenya kweganda, uye kusimbisa bvudzi nekupenya uye nehuwandu.
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Yepamusoro yemhando yakachena yakasikwa Notopterygium oiri inoshandiswa kuUtano hwekuchengetedza
Panyaya yekudzinga mhepo uye kubvisa kunyorova, kune akawanda anokodzera maChinese herbs. Nokudaro, kuenzanisa notopterygium nevezera rayo vane maitiro ekuporesa akafanana zvingatibatsira kunzwisisa chirimwa chemishonga iyi zviri nani.
Ose ari maviri notopterygium mudzi uye Angelica Root (Du Huo) inogona kujekesa mhepo-inonyorova uye inovandudza marwadzo emajoini uye kuoma. Asi ivo vane zvavanogona uye zvavanotadza zvichiteerana. Iyo yekutanga ine hunhu hwakasimba uye kuravira, izvo zvinoita kuti ive nani antipyretic mhedzisiro kuburikidza nekudikitira uye kukwira potency. Nokuda kwechikonzero ichocho, ihwo huripo hwakanaka hwezvirwere zvemusana uye kurwadziwa kwepamusoro pemuviri uye kumashure kwemusoro. Mukuenzanisa, angelica midzi ndeyekudzika potency, iyo inoiisa simba rekuporesa riri nani pane rheumatism yemuviri wepazasi uye kurwadziwa kwemajoini mutsoka, kuzasi kumashure, gumbo, uye shin. Nekuda kweizvozvo, iwo anowanzo shandiswa ari maviri emushonga nekuti iwo anonyatso pindirana.
Zvose notopterygium uyeGui Zhi (Ramulus Cinnamomi)dzakanaka pakudzinga mhepo nekubvisa chando. Asi iyo yekare inofarira mhepo-inonyorova mumusoro, mutsipa, uye kumashure nguvaGui Zhizviri nani kubata nemhepo-inonyorova mumapfudzi, maoko, uye zvigunwe.
Bothe notopterygium uyeFang Feng (Radix Saposhnikoviae)vane hunyanzvi hwekudzinga mhepo. Asi iyo yekutanga ine simba rakasimba kupfuura Fang Feng.
Mazuva ano pharmacological zviito zve notopterygium mudzi
1. Jekiseni rayo rine analgesic uye antipyretic madhara. Mukuwedzera, ine inhibition paganda fungus uye brucellosis;
2. Chikamu chayo chinonyungudika chine kuedza anti-arrhythmic effect;
3. Mafuta ayo anopisa anewo anti-inflammatory, analgesic uye antipyretic madhara. Uye inogona kurwisana nepituitrin-induced myocardial ischemia uye kuwedzera myocardial nutritional blood flow;
4. Mafuta ayo anoputika achiri kurambidza kunonoka mhando hypersensitivity mumakonzo.Sample notopterygium incisum recipes pamishonga yemakwenzi
Zhong Guo Yao Dian (Chinese pharmacopoeia) anotenda kuti inovava uye inovava mukunaka uye inodziya mumasikirwo. Inovhara meridians ye bladder uye itsvo. Mabasa makuru kudzinga mhepo, kubvisa kutonhora, kubvisa hunyoro, uye kubvisa marwadzo. Basic notopterygium inoshandisa uye zviratidzo zvinosanganisiramusoromumhando yemhepo-inotonhoradzihwa, rheumatism, uye kurwadziwa kwepfudzi uye musana. Inokurudzirwa dosi kubva pa3 kusvika ku9 gramu.
1. Qiang HuoFu ZiTang kubva kuYi Xue Xin Wu (Zviratidzo zveMedical). Yakasanganiswa neFu Zi (Aconite),Gan Jiang(Dried GingerRoot), uye ZhiGan Cao(Honey Fried Licorice Root) kurapa huropi hwakarwiswa nekunze kwechando pathogen, marwadzo ehuropi anobuda kumazino, mitezo inotonhora, uye mweya unotonhorera kubva mumuromo nemumhino.
2. Jiu Wei Qiang Huo Tang kubvaCi ShiNan Zhi (Ruzivo rwakaoma-Won). Yakagadzirwa neFang Feng, Xi Xin (Herba Asari),Chuan Xiong(lovage root), nezvimwewo kurapa mhepo-inotonhora yekunze hutachiona hunoperekedzwa nekunyorova, kutonhora, fivha, pasina ziya, musoro,mitsipa yakaoma, uye kurwadza kwemajoini kwakapinza mumakumbo.
3. Qiang Huo Sheng Shi Tang kubva kuNei Wai Shang Bian Huo Lun (Kujekesa Kusava nechokwadi pamusoro peKukuvadzwa kubva Mukati uye Kunze Zvikonzero). Inoshandiswa pamwe chete neangelica mudzi,Gao Ben(Rhizoma Ligustici), Fang Feng, nezvimwewo kurapa kunze kunyorova nemhepo, kutemwa nemusoro uye kurwadza kwakasimba nape, kuvava kunorema kuzasi kunorwadza, uye muviri wese kurwadziwa kwemajoini.
4. Juan Bi Tang, anozivikanwawo se notopterygium uyeturmericmusanganiswa, kubva kuBai Yi Xuan Fang (Zvakanyatsosarudzwa-Zvakasarudzwa). Inoshanda naFang Feng, Jiang Huang (Curcuma Longa),Dang Gui(Dong Quai), nezvimwewo kugumisa mhepo-kutonhora-kunyorova arthralgia mumuviri wepamusoro, kurwadziwa mukubatana kwefudzi nemakumbo.
5. Qiang Huo Gong Gao Tang kubva kuShen Shi Yao Han (Bhuku Rinokosha reOphthalmology) Inobatana nemudzi welovage,Bai Zhi(Angelica Dahurica), Rhizoma Ligustici, etc. kuzorodza musoro unokonzerwa nemhepo-inotonhora kana mhepo-inonyorova.
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Yakachena Aucklandia lappa mafuta ekenduru uye sipo kugadzira wholesale diffuser yakakosha mafuta matsva ekupisa tsanga diffuser.
Osteoarthritis (OA) ndechimwe chenguva refu chisingaperi chisingaperi chechirwere chemapfupa chejoini chinobata vanhu vakwegura vanopfuura 65 [1]. Kazhinji, varwere veOA vanoonekwa kuti vane cartilage yakakuvadzwa, inoputika synovium, uye eroded chondrocytes, izvo zvinokonzera marwadzo uye kushungurudzika mumuviri [2]. Marwadzo eArthritic anonyanya kukonzerwa nekuderera kwecartilage mumajoini nekuzvimba, uye kana cartilage yakuvadzwa zvakanyanya mapfupa anogona kudhumhana zvichikonzera kurwadziwa kusingatsungirike uye kuoma kwemuviri [3]. Kubatanidzwa kwevamiriri vezvipembenene vane zviratidzo zvakadai sekurwadziwa, kuzvimba, uye kuoma kwekubatana kwakanyatsonyorwa. Mune varwere veOA, cytokines inoputika, iyo inokonzera kuputika kwecartilage uye subchondral bone inowanikwa mu synovial fluid.4]. Zvichemo zviviri zvikuru izvo varwere veOA vanowanzova nazvo kurwadziwa uye kuzvimba kwe synovial. Naizvozvo zvibodzwa zvekutanga zveazvino OA marapiro ndeekudzikisa marwadzo nekuzvimba. [5]. Kunyange zvazvo mishonga yeOA iripo, kusanganisira isiri-steroidal uye steroidal zvinodhaka, zvakaratidza kushanda mukuderedza marwadzo uye kuzvimba, kushandiswa kwenguva refu kwemishonga iyi kune hutano hwakanyanya hwehutano hwakadai semwoyo, gastro-intestinal, uye renal dysfunctions [6]. Saka, mushonga unoshanda une mashoma mhedzisiro unofanirwa kugadzirwa pakurapa osteoarthritis.Zvigadzirwa zvehutano zvechisikigo zviri kuwedzera kufarirwa kuve zvakachengeteka uye kuwanikwa zviri nyore [7]. Mishonga yechinyakare yekuKorea yakaratidza kushanda kwayo kurwisa zvirwere zvakawanda zvinopisa, kusanganisira arthritis [8]. Aucklandia lappa DC. inozivikanwa nemishonga yayo, yakadai sekusimudzira kutenderera kwe qi yekubvisa marwadzo nekunyaradza dumbu, uye yave ichishandiswa sechinyakare seanalgesic yechisikigo [9]. Mishumo yapfuura inoratidza kuti A. lappa ine anti-inflammatory [10,11], analgesic [12], anticancer [13], uye gastroprotective [14] migumisiro. Zvinhu zvakasiyana-siyana zvehupenyu zveA lappa zvinokonzerwa nemishonga yayo mikuru inoshanda: costunolide, dehydrocostus lactone, dihydrocostunolide, costuslactone, α-costol, saussurea lactone uye costuslactone [15]. Zvidzidzo zvepakutanga zvinoti costunolide yakaratidza anti-inflammatory properties mu lipopolysaccharide (LPS), iyo yakakonzera macrophages kuburikidza nekugadzirisa kweNF-kB uye kupisa kunotyisa kweprotein nzira [16,17]. Zvakadaro, hapana ongororo yakaongorora zvinogona kuitika zveA. lappa pakurapwa kweOA. Tsvagiridzo yazvino yakaongorora marapirwo eA. lappa kurwisa OA vachishandisa (monosodium-iodoacetate) MIA neacetic acid-induced rodent modhi.Monosodium-iodoacetate (MIA) inonyanya kushandiswa kugadzira maitiro mazhinji ekurwadziwa uye pathophysiological maficha eOA mumhuka.18,19,20]. Kana ichiiswa mumajoini emabvi, MIA inoparadza chondrocyte metabolism uye inokonzera kuzvimba uye zviratidzo zvinoputika, zvakadai sekartilage uye subchondral bone erosion, cardinal zviratidzo zveOA [18]. Writhing mhinduro inokonzerwa neacetic acid inotaridzirwa zvakanyanya sekuenzanisa kwekurwadziwa kwepamuviri mumhuka umo kurwadziwa kwekuputika kunogona kuyerwa zvakanyanya [19]. Iyo mbeva macrophage cell line, RAW264.7, inonyanya kushandiswa kudzidza mhinduro dzemaserura pakuzvimba. Paunenge uchishandiswa neLPS, RAW264 macrophages inoshandisa nzira dzekuvhiringidza uye inobudisa vatsigiri vakawanda vanopisa, seTNF-α, COX-2, IL-1β, iNOS, uye IL-6 [20]. Ichi chidzidzo chakaongorora maitiro e-anti-nociceptive uye anopesana nekuputika kweA. lappa inopesana neOA muMIA mhuka yemuenzaniso, acetic acid-induced animal model, uye LPS-activated RAW264.7 masero.2. Zvishandiso uye Nzira
2.1. Plant Material
Mudzi wakaomeswa weA. lappa DC. yakashandiswa mukuyedza yakatengwa kubva kuEpulip Pharmaceutical Co., Ltd., (Seoul, Korea). Yakaonekwa naProf. Donghun Lee, Dhipatimendi reHerbal pharmacology, Col. weKorea Medicine, Gachon University, uye nhamba yevhoti yemuenzaniso yakaiswa se18060301.2.2. HPLC Analysis yeA. lappa Extract
A. lappa yakabudiswa uchishandisa reflux apparatus (mvura yakasvibiswa, 3 h pa100 ° C). Mushonga wakabudiswa wakanatswa uye wakaderedzwa uchishandisa low-pressure evaporator. A. lappa extract yakava negoho re44.69% mushure mekuomesa nechando pasi pe −80 °C. Chromatographic analysis yeA. lappa yakaitwa neHPLC yakabatana uchishandisa 1260 InfinityⅡ HPLC-system (Agilent, Pal Alto, CA, USA). Pakuparadzaniswa kwechromatic, EclipseXDB C18 column (4.6 × 250 mm, 5 µm, Agilent) yakashandiswa pa35 °C. Zvose zve 100 mg yemuenzaniso yakaderedzwa mu 10 mL ye 50% methanol uye sonicated ye 10 min. Samples dzakasefa nesirinji sefa (Waters Corp., Milford, MA, USA) ye0.45 μm. Kuumbwa kwechikamu chekufambisa kwaiva 0.1% phosphoric acid (A) uye acetonitrile (B) uye koramu yakabudiswa sezvinotevera: 0-60 min, 0%; 60–65 min, 100%; 65–67 min, 100%; 67-72 min, 0% solvent B ine kuyerera kwe 1.0 mL / min. Iyo tsvina yakaonekwa pa210 nm uchishandisa jekiseni vhoriyamu ye10 μL. Ongororo yacho yakaitwa mumatatu.2.3. Kugara Kwemhuka uye Kutarisira
Murume Sprague-Dawley (SD) makonzo ane mavhiki e5 uye mbeva dzechirume dzeICR dzine masvondo matanhatu dzakatengwa kubva kuSamtako Bio Korea (Gyeonggi-do, Korea). Mhuka dzaichengetwa mukamuri uchishandisa tembiricha nguva dzose (22 ± 2 ° C) uye humidity (55 ± 10%) uye chiedza / rima kutenderera kwe12/12 h. Mhuka idzi dzaizivikanwa nemamiriro acho kweinopfuura vhiki isati yatanga kuedza. Mhuka dzaive nead libitum yekudya uye mvura. Mitemo yezvino yehutsika yekuchengetwa kwemhuka uye kubata paGachon University (GIACUC-R2019003) yakatevedzwa zvakatsiga mune ese mhuka yekuedza maitiro. Chidzidzo chacho chakagadzirirwa muongorori-akapofumadzwa uye kuyedza kwakafanana. Isu takatevera nzira ye euthanasia maererano nemirairo ye Animal Experimental Ethics Committee.2.4. MIA Jekiseni uye Kurapa
Makonzo akapatsanurwa zvisina tsarukano kuita mapoka mana, anoti sham, control, indomethacin, uye A. lappa. Kuve anesthetized ne 2% isofluorane O2 musanganiswa, makonzo akaiswa jekiseni achishandisa 50 μL yeMIA (40 mg / m; Sigma-Aldrich, St. Louis, MO, USA) intra-articularly mumabvi akabatanidzwa kuti atungamirire kuedza OA. Mishonga yakaitwa senge pazasi: kutonga uye mapoka esham aichengetwa chete neAIN-93G yakakosha kudya. Chete, boka reindomethacin rakapiwa indomethacin (3 mg/kg) yakabatanidzwa muAIN-93G kudya uye A. lappa 300 mg/kg boka rakapiwa kuAIN-93G kudya kwakawedzerwa neA. lappa (300 mg/kg). Mishonga yakaenderera mberi kwemazuva makumi maviri nemana kubva pazuva reOA induction pamwero we15-17 g pa190-210 g uremu hwemuviri pazuva.2.5. Kuyera Kutakura Kuyera
Mushure meOA induction, kuyerwa kwehuremu hwehuremu hwemashure emakonzo akaitwa ne incapacitance-MeterTester600 (IITC Life Science, Woodland Hills, CA, USA) sezvakarongwa. Huremu kugoverwa pamakumbo eshure kwakaverengerwa: huremu hwekuremerwa simba (%) -
Chinese Angelica Dahurica Root Extract Oil for Massage
Kushandiswa kweAngelica
Kushandiswa kwekuwedzera kunofanirwa kuve kwakasarudzika uye kuongororwa nenyanzvi yezvehutano, senge akanyoreswa dhietitian, wemishonga, kana mutapi wehutano. Hapana chekuwedzera chinoitirwa kurapa, kurapa, kana kudzivirira chirwere.
Humbowo hwakasimba hwesainzi hunotsigira kushandiswa kweAngelica hunoshaikwa. Kusvika pari zvino, yakawanda yekutsvagisa pamusoroAngelica archangelicayakaitwa pamhando dzemhuka kana mumarabhoritari. Pakazara, miedzo yakawanda yevanhu inodiwa pane zvingangobatsira zveAngelica.
Izvi zvinotevera kutarisa izvo tsvakiridzo iripo inoti maererano nekushandiswa kweAngelica.
Nocturia
NocturiaChirwere chinotsanangurwa sechido chekumuka kubva kuhope kamwechete kana kupfuura usiku hwega hwega kuti uite weti. Angelica yakadzidzwa kushandiswa kwayo mukubvisa nocturia.
Mune imwe ongororo yemapofu maviri, vatori vechikamu vane nocturia vakapihwa murume pakuzvarwa vakarongeka kuti vagamuchire cheroplacebo(chinhu chisingabatsiri) kana chigadzirwa chakagadzirwa kubva kuAngelica archangelicashizha kwemavhiki masere.4
Vatori vechikamu vakakumbirwa kuti vatarise mumadhayari kana ivoweti. Vatsvakurudzi vakaongorora madhayari zvose zvisati zvaitika uye shure kwenguva yekurapa. Pakupera kwechidzidzo, avo vakatora Angelica vakashuma mashoma emasikati (kudiwa kwekumuka pakati peusiku kuti aite weti) pane avo vakatora placebo, asi musiyano wakanga usina kukosha.4
Zvinosuruvarisa, zvimwe zvidzidzo zvishomanana zvakaitwa kuti zvione kana Angelica anogona kuvandudza nocturia zvakanyanya. Kutsvakurudza kwakawanda kunodiwa munzvimbo iyi.
Kenza
Kunyange pasina chekuwedzera kana miriwo inogona kurapakenza, kune kumwe kufarira kuna Angelica senzira yekuwedzera.
Vatsvagiri vakadzidza Angelica anogona kuita anticancer mhedzisiro murabhoritari. Mune kumwe kuongorora kwakadaro, vatsvakurudzi vakaedzaAngelica archangelicaextract onkenza yemazamumasero. Vakaona kuti Angelica anogona kubatsira kukonzera kenza yemazamu kufa, zvichiita kuti vatsvakurudzi vafunge kuti mushonga unogona kuva nawoantitumorzvinogona.5
Chidzidzo chekare chakaitwa pamakonzo chakawana mhedzisiro yakafanana.6 Zvisinei, izvi zvabuda hazvina kudzokororwa mukuedzwa kwevanhu. Pasina miedzo yevanhu, hapana humbowo hwekuti Angelica anogona kubatsira kuuraya maseru egomarara remunhu.
Kuzvidya mwoyo
Angelica yakashandiswa mumishonga yechivanhu semushonga wekufunganya. Zvisinei, humbowo hwesainzi hunotsigira chirevo ichi hushoma.
Sezvimwe nemamwe mashandisirwo eAngelica, tsvakiridzo yekushandiswa kwayo mukushushikana kwakanyanya kuitwa mumarabhoritari kana pamhando dzemhuka.
Mune imwe ongororo, Angelica zvinyorwa zvakapihwa makonzo vasati vaitastressmiedzo. Maererano nevatsvakurudzi, makonzo akaita zviri nani mushure mokugamuchira Angelica, zvichiita kuti ive inogona kurapwa kwekuzvidya mwoyo.7
Miedzo yevanhu uye kutsvagisa kwakasimba kunodiwa kuti uone kuti Angelica angaite basa rekurapa kusagadzikana.
Antimicrobial Properties
Angelica anonzi ane antimicrobial properties, asi zvidzidzo zvevanhu zvakanyatsogadzirwa hazvina kuitwa kuratidza izvi.
Sekureva kwevamwe vaongorori, Angelica inoratidza antimicrobial chiitiko ichipokana ne:2
- Clostridium difficile (C. zvakasiyana)
- Clostridium perfringens
- Enterococcus faecalis
- Eubacterium limosum
- Peptostreptococcus anaerobius
- Candida albicans
Nekudaro, zvishoma zvinyorwa zvinopihwa maererano nemabatiro anoita Angelica aya nemamwe mabhakitiriya nefungi.
Zvimwe Zvishandiso
Mumishonga yechivanhu,Angelica archangelicainoshandiswa kurapa zvimwe zvirwere, kusanganisira:1
Humbowo hwesainzi hwemhando yepamusoro hunotsigira kushandiswa uku hushoma. Iva nechokwadi chekutaura nemupi wehutano usati washandisa Angelica kune izvi uye mamwe mamiriro ehutano.
Ndezvipi Zvikonzero zveAngelica?
Sezvakaita chero miriwo kana yekuwedzera, Angelica inogona kukonzera mhedzisiro. Nekudaro, nekuda kwekushaikwa kwemiedzo yevanhu, kwave kune mishumo mishoma yezvinobvira zvinokonzerwa neAngelica.
