Yakachena organic organic magnolia yakakosha mafuta flos magnoliae mafuta emafuta ekunhuhwirira
Magnoliae Flos inowanzoshandiswa mishonga yechivanhu muAsia. Inoshandiswa kurapa sinusitis, nasal congestion, uye hypersensitive ganda. Nekuti Magonlia Flos yaitsanangurwa sechinhu chinonhuhwirira muzvinyorwa zvekare zvechiChinese, isu takafungidzira kuti mafuta ayo akakosha anogona kushandiswa kurapa immune immune. Dendritic masero (DCs), anoonekwa sechinangwa chikuru chevanodzivirira zvirwere zvekudzivirira zvirwere zvekudzivirira zvirwere, vanoita basa rinokosha mukugadzirisa kwekudzivirira zvirwere. Muchidzidzo ichi, Magnoliae Flos mafuta anokosha (MFEO) akaderedza kugadzirwa kwe cytokines TNF-α" role = "presentation" style = "box-size: border-box; kuratidza: inline; mutsara-urefu: zvakajairika; izwi-spacing: zvakajairika; kufashukira-kuputira: zvakajairika; white-space: nowrap; kuyangarara: hapana; nzira: ltr; max-width: hapana; max-urefu: hapana; min-upamhi: 0px; min-kureba: 0px; muganhu: 0px; padding: 0px; kumucheto: 0px; chinzvimbo: hama;”>α
, IL-6, uye IL-12p70 mu lipopolysaccharide (LPS) -inosimudzira DCs. Yakadzvanya zvakare mamaki epamusoro MHC II, CD80, uye CD86 muLPS-inosimudzira DCs. Mienzaniso yemhuka yakaratidza kuti 2,4-Dinitro-1-fluorobenzene (DNFB) inokonzera kusangana ne hypersensitivity mhinduro yakadziviswa kutevera kurapwa neMFEO. Mukuwedzera, MFEO yakadzivisa kupinda kwemasero eT munzeve dzeDNFB-induced mice. Kuti uongorore bioactive makomisheni ayo, zvikamu zveMFEO zvakaongororwa uchishandisa gasi chromatography (GC) uye GC-mass spectrometry. Mhedzisiro yacho yakaratidza kuti makomba makuru muMFEO ndeye camphor uye 1,8-cineole. Kuwedzera DC bioassays yakasimbisa kuti aya makomisheni akanyanya kudzvanya kugadzirwa kwe cytokine muLPS-induced DCs. Naizvozvo, takaratidza kuti MFEO inoratidza immunosuppressive maitiro ese ari maviriin vivouyein vitro, uye camphor uye 1,8-cineole inogona kunge iri iyo huru yezvikamu zvinokonzerwa nekukwanisa kwayo immunosuppressive. Zvakawanikwa zvinoratidza kuti MFEO ine mukana wekugadzirwa semushonga wekudzivirira zvirwere zvakanyanya.